As of 12/17/2021, Ortho Product Supplements are not available to be ordered online. We are working on a resolution for the current situation In the interim, to purchase this item please email email@example.com or call out office at (248)347-5800. If you keep a credit card on file at our Office, that card will be charged. The cost of this item is $20.00.
Seleno-Iodide is designed to provide key nutrients for optimal thyroid and breast health.
Seleno-Iodide provides a synergistic blend of iodine, along
with its trace mineral partner selenium, to help maintain iodine
levels and reduce oxidative stress for optimal thyroid and
breast health. Seleno-Iodide provides 3 mg of iodine combined
with 100 mcg of selenium sourced from SelenoExcellŽ, a highly
bioavailable, organically bound selenium.
Iodine is an essential trace mineral found in various forms in
nature and is necessary for human growth and development.
Dietary sources of iodine include seafood, seaweeds including
wakame and nori, navy beans, potatoes, and iodized salt.
Approximately 15 to 20 mg of iodine is concentrated in the
thyroid gland in a healthy human body.
Iodine is necessary for the
synthesis of thyroid hormones, as it is one of the most important
components of the hormones thyroxine (T4) and tri-iodothyronine
(T3). T3 is the most active thyroid hormone and binds to receptors
in the liver and brain to regulate gene expression.
In addition to supporting thyroid hormone production,
research shows iodine acts as an antioxidant, supporting
a healthy thyroid gland and protecting a variety of tissues,
including mammary tissue, the eyes and gastrointestinal
In other tissues, such as the mammary glands, the
protective role of iodine is connected to its antioxidant
function. Iodide can act as an electron donor in the presence
of hydrogen peroxide and peroxidase, thereby decreasing
damage by free oxygen radicals (Figure 1). In research studies,
serum concentrations of iodine as low as 15 micromolar have
demonstrated comparable antioxidant activity to vitamin C.
Selenium is a trace mineral required to produce several
important compounds, including enzymes involved in
antioxidant mechanisms and thyroid hormone metabolism.
Selenium intake depends largely on soil conditions in the
region where food is grown or raised. Food sources of
selenium include Brazil nuts, eggs, peas, poultry and meats.
SelenoExcellŽ is a bioavailable, organic selenium supplement
that is closest to forms found in nature.
Under-functioning of the thyroid has been found to be
common in regions where selenium deficiency rates are
Selenium is crucial in supporting thyroid health, as
it is a required cofactor for three key enzymes involved in
the production of thyroid hormones, the iodothyronine
deiodinases. Iodothyronine deiodinases catalyze the release
of iodine from T4 to T3, allowing for increased production of
the more metabolically active thyroid hormone T3 (Figure 1).
Low plasma selenium concentrations have been found to be
associated with impaired conversion of T4 to T3.
The thyroid gland is a highly metabolically active tissue in which
oxidative processes are indispensable for thyroid hormone
synthesis. This is namely because that the thyroid naturally
produces large amounts of hydrogen peroxide (H2
O2). Hydrogen peroxide is a necessary substrate for thyroid peroxidase (TPO),
an enzyme expressed mainly in the thyroid, which plays a major
role in thyroid hormone synthesis .
Under healthy physiological conditions, a balance between
the generation and detoxification of free radicals is maintained.
A powerful antioxidant enzyme system is activated to ensure
the thyroid is protected from ongoing free radical production.
Glutathione is one of the key antioxidants used to neutralize free
radicals in the thyroid. Glutathione, requires selenium to activate
the enzyme glutathione peroxidase (GPX). Selenium-containing
GPX in the thyroid cell plays a pivotal role in maintaining normal
thyroid functioning by protecting the gland from oxidative
stress by removing excess H2O2
from the tissues. Subsequently,
supplementation with selenium has been shown to modify
inflammatory and immune responses in patients with immune
challenges and decrease TPO antibodies.
The breast and ovaries also concentrate high amounts of
iodine. Iodine plays a vital role in supporting the structure and
function of the mammary glands. In animal studies, iodine
deficiency has been connected to an alteration in the structure
and function of mammary glands. In a randomized, doubleblind, placebo-controlled trial, 111 subjects were recruited to examine the effects of iodine administration on breast health
in women with normal thyroid function. Following three
months of treatment, a statistically significant improvement in
breast comfort was observed in the groups receiving 3 or 6 mg
of iodine per day compared to placebo.
1 capsule per day or as recommended by your health care
Each Bottle contains 90 capsules